NCT05830695

Evaluation of Apexogenesis With Human Treated Dentin Matrix in Young Permanent Molars

Clinical, Radiographic and Tomographic Evaluation of Apexogenesis With Human Treated Dentin Matrix in Young Permanent Molars

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: nora mostafa mohammed abo shanady · Academic / Other
• Sex: All
• Age: 6 Years – 8 Years
• Healthy volunteers: Accepted

Summary

Assess the clinical, radiographic, and tomographic outcomes of apexogenesis with human treated dentin matrix in young permanent molars compared to MTA.

Detailed description

The study was conducted as a split-mouth randomized clinical trial, approved by research ethics committee, Faculty of Dentistry, Tanta University, and carried out at Pediatric Dentistry Department, Faculty of Dentistry, Tanta University. The material preparation was conducted at Pharmaceutical Technology Department, Faculty of Pharmacy, Tanta University. 20 children of both sexes aged from 6 to 8 years old were selected with bilateral deeply carious young permanent mandibular first molars that are indicated for vital pulp therapy.The selected deeply carious molars were randomly divided into two groups as follows: Group I (Study group): 20 molars were treated with human TDM. Group II: (Control group): 20 molars were treated with White MTA. The participating cases were evaluated clinically and radiographically after 6, 12 and 18 months. Tomographic evaluation was performed immediate postoperatively and at 18 months.

Conditions

• Dentin Bridge

Interventions

Type	Name	Description
DRUG	human treated dentin matrix	human treated dentin matrix is compared with mineral trioxide aggregate in apexogenesis
DRUG	Mineral Trioxide Aggregate	mineral trioxide aggregate was used as control

Timeline

• Start date: 2022-01-18
• Primary completion: 2022-07-18
• Completion: 2023-03-31
• First posted: 2023-04-26
• Last updated: 2024-07-30

Locations

1 site across 1 country: Egypt