Trials / Active Not Recruiting
Active Not RecruitingNCT05828680
Circadian Rhythm Disruption in the Hospital Intensive Care Environment
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 15 (estimated)
- Sponsor
- University of Pennsylvania · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
Abrupt changes to one's lifestyle disrupt biorhythms. Acute effects are well known from jet lag where transmeridian travel leads to insomnia, fatigue, irritability, gastrointestinal symptoms and other complaints. Several studies in the hospital environment reported dampened and misaligned biorhythms, suggesting that the inpatient experience is replete with circadian disruptors. However, comprehensive assessments of how circadian clocks are affected in intensive care and how this predicts post-operative recovery and risk are largely missing.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Observation | No intervention |
Timeline
- Start date
- 2023-03-15
- Primary completion
- 2027-12-01
- Completion
- 2028-12-01
- First posted
- 2023-04-25
- Last updated
- 2026-01-23
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05828680. Inclusion in this directory is not an endorsement.