NCT05825664

Underwater Versus Conventional Endoscopic Mucosal Resection in the Treatment of Non-pedunculated Colorectal Polyps

Comparison of the Efficiency and Safety of Underwater Endoscopic Mucosal Resection and Conventional Endoscopic Mucosal Resection in the Treatment of Non-pedunculated Colorectal Polyps

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 228 (estimated)
• Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A prospective, randomized, controlled study to compare the efficacy and safety of underwater endoscopic mucosal resection and conventional endoscopic mucosal resection in removal of non-pedunculated colorectal polyps

Detailed description

* Patients are undergone colonoscopy at the Endoscopy department of Ho Chi Minh City University Medical Center. * Randomize patients with non-pedunculated polyp of 10mm or larger in size into 2 interventional groups based on Random function of Statistical Package for the Social Sciences (SPSS) 20.0, including (1) Group 1: Underwater endoscopic mucosal resection (UEMR) and (2) Group 2: Conventional endoscopic mucosal resection (CEMR). * The time of local recurrence assessment depends on the histopathology of polyps. Polyps with low grade dysplasia are followed up at 6 months, while polyps with high grade dysplasia are followed at 3 months. * Collecting variables which consist of primary and secodary outcomes.

Conditions

• Colorectal Polyp
• Colorectal Neoplasms

Interventions

Type	Name	Description
PROCEDURE	Endoscopic resection	Group 1: Polyps are resected by UEMR Group 2: Polyps are resected by CEMR

Timeline

• Start date: 2023-04-07
• Primary completion: 2023-12-31
• Completion: 2024-07-31
• First posted: 2023-04-24
• Last updated: 2023-04-24

Locations

1 site across 1 country: Vietnam