NCT05823441

Effect of Oxytocin Nasal Inhalation on Empathy Analgesia

Effects of Oxytocin Nasal Inhalation and Social Familiarity on Empathy Analgesia: a Factorial Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

This study recruited healthy volunteers and randomly divided them into four groups. They inhaled oxytocin or saline, and watched a pain test video with photos of acquaintances or strangers, respectively, to test whether their feelings of the same thermal pain stimulus had changed.

Conditions

• Oxytocin
• Pain
• Empathy
• Social Familiarity
• Analgesia

Interventions

Type	Name	Description
DRUG	Oxytocin nasal spray	Volunteers inhale 24 units of oxytocin spray
DRUG	Placebo	Volunteers inhale 24 units of placebo spray
BEHAVIORAL	Stranger	Volunteers watch a video of a pain test and attach a photo of a stranger
BEHAVIORAL	Acquaintance	Volunteers watch a video of a pain test and attach a photo of an acquaintance

Timeline

• Start date: 2023-06-03
• Primary completion: 2024-01-21
• Completion: 2024-01-21
• First posted: 2023-04-21
• Last updated: 2024-02-01

Locations

1 site across 1 country: China