NCT05821400

Cognitive Changes in Mild Cognitive Impairment

Cognitive Changes in Mild Cognitive Impairment Without Orthostatic Hypotension

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Fujian Medical University Union Hospital · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Background: In recent years, the changes of cognitive function in mild cognitive impairment have attracted attention. Methods/design: We will follow up at 3. The primary outcome will be the measurement of cognitive function using neuropsychological assessment scales such as MOCA, MMSE, etc... Minor variables will be included plasma biomarkers (Aβ, Tau, GFAP, etc.), multimodal brain electrophysiology (P300, VP300, heart rate variability, etc.), and neuroimaging indicators (NODDI).

Conditions

• Healthy Controls Without Orthostatic Hypotension

Interventions

Type	Name	Description
OTHER	observational study	observational study

Timeline

• Start date: 2023-03-01
• Primary completion: 2024-04-30
• Completion: 2024-06-30
• First posted: 2023-04-20
• Last updated: 2023-04-20

Locations

1 site across 1 country: China