NCT05819619

Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days

• Status: Terminated
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Hackensack Meridian Health · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Randomized trial which will aim to evaluate whether prophylactic use of ondansetron and ibuprofen will decrease side effects associated with medical abortion and increase patient satisfaction.

Conditions

• Nausea
• Pain

Interventions

Type	Name	Description
DRUG	Prophylactic use of ibuprofen and ondansetron post misoprostol administration	Prophylactic use of ibuprofen and ondansetron post misoprostol administration
DRUG	Use of ibuprofen and ondansetron at symptom onset post misoprostol administration	Administration of ibuprofen or ondansetron only when experiencing pain or nausea respectively post misoprostol administration.

Timeline

• Start date: 2023-07-20
• Primary completion: 2024-04-01
• Completion: 2024-04-11
• First posted: 2023-04-19
• Last updated: 2025-11-17
• Results posted: 2025-11-17

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study