NCT05818358

Postprandial Effects of Bean and Whole Grain Consumption on Arterial Stiffness

A Pilot Study to Examine the Effect of Consuming Beans and Whole Grains at Breakfast on Postprandial Vascular Responses in People With Arterial Stiffness

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: University of Manitoba · Academic / Other
• Sex: All
• Age: 45 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This is a single site, single-blinded, controlled randomized crossover clinical trial designed to compare the effects of black beans or whole grains or white rice at breakfast on postprandial vascular responses in males and females with arterial stiffness (n=10). Eligible participants will be asked to attend 3 in-person visits for comparative testing of black beans versus whole grains versus white rice.

Detailed description

This is a single site, single-blinded, randomized, controlled crossover study designed to compare the vascular responses of males and females with arterial stiffness before and 2 hours after ingestion of black beans or whole grains (wheat) or white rice (isocaloric comparator). Recruitment will consist of a total of 10 participants with arterial stiffness. Participants will be recruited through advertisement from the local community. The study will be conducted at the Asper Clinical Research Institute, St. Boniface Hospital. Participants will be asked to provide written informed consent prior to participation in the study. Participants who have provided written consent will be asked to attend an in-patient screening visit to provide a fasting blood sample (and females a urine sample) and assess the presence of arterial stiffness (by PWV) to determine eligibility. Should the participant be eligible to participate, they will be scheduled for three study visits to obtain fasting blood samples and assess postprandial blood vessel function. During the first study visit period, participants will be asked to complete a Food Habits Questionnaire.

Conditions

• Arterial Stiffness

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	black beans	¾ cup of cooked black beans
DIETARY_SUPPLEMENT	wheat berries	¾ cup of cooked whole wheat grain
DIETARY_SUPPLEMENT	white rice	¾ cup of cooked white rice

Timeline

• Start date: 2023-04-01
• Primary completion: 2024-03-22
• Completion: 2024-04-30
• First posted: 2023-04-18
• Last updated: 2025-02-28

Locations

1 site across 1 country: Canada