NCT05817526

BMAC Loaded Collagen Jumping the Gap Around Immediate Implants

Assessment of Collagen Loaded With Bone Marrow Aspirate Concentrate Versus Autograft on Marginal Bone Changes Around Immediate Implants in Esthetic Zone. A Randomized Controlled Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The present study aims to evaluate the effect of utilization of BMAC/ collagen on marginal bone changes around immediate implants in the esthetic zone of maxilla. Methodology: Twenty dental implants will be installed in the esthetic zone and patients will be randomly divided into two groups: study group: The jumping gap surrounding the immediate implants will be grafted with BMAC/collagen, whereas in the control group, autograft from the chin will be used to fill the defect. Cone beam CT (CBCT) will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around implants. .

Detailed description

The aim of present study is to evaluate the effect of utilization of bone marrow aspirate concentrate (BMAC) loaded on collagen on the marginal bone changes around immediate implants in the esthetic zone of maxilla. Methodology: Twenty dental implants will be installed in patients suffering from non- restorable teeth in esthetic zone. Patients will be randomly divided into two equal groups: study group: The jumping gap surrounding the immediate implants will be grafted with bone marrow aspirate concentrate loaded on collagen, whereas in the control group, autogenous bone graft from the chin will be used to fill the peri-implant defect. CBCT will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around dental implants. .

Conditions

• Implant Site Reaction
• Dental Implantation

Interventions

Type	Name	Description
DRUG	BMAC/ collagen	Bone marrow aspirate concentrate loaded on collagen in the peri-implant defect
PROCEDURE	Autograft harvesting from chin	Autograft

Timeline

• Start date: 2023-01-25
• Primary completion: 2024-10-01
• Completion: 2024-12-01
• First posted: 2023-04-18
• Last updated: 2024-03-28

Locations

1 site across 1 country: Egypt