NCT05817266

Role of FCI in the Detection of Proctosigmoiditis Caused by IBD

Role of Field-Cycling Imaging in the Detection of Proctosigmoiditis Caused by Inflammatory Bowel Disease

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: NHS Grampian · Other Government
• Sex: All
• Age: 16 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The goal of this pilot study is to explore the ability of field-cycling imaging, a new scanning technology being developed at the University of Aberdeen, to detect active disease in patients with proctosigmoiditis caused by inflammatory bowel disease.

Detailed description

Field-cycling imaging (FCI) is an emerging technology that is being developed at the University of Aberdeen. It combines the use of a moderately high magnetic field (200mT) with the ability to probe low magnetic fields (0.2mT) so that image resolution can be preserved while also exploiting the high contrast present at low magnetic fields. This non-invasively provides quantitative data on the molecular dynamics in the tissues. FCI represents a potentially new, non-invasive, way of assessing the extent and activity of inflammatory bowel disease (IBD). IBD can affect the rectum and distal sigmoid colon, this condition is called Proctosigmoiditis (PS). Currently, diagnosis of IBD depends on endoscopy for direct visualisation of the upper and lower gut, using CT scanning, with its attendant use of ionising radiation, and conventional MRI, particularly for the small bowel. Determining the activity of IBD remains a continuing challenge. In this proof-of-concept study, the investigators will explore the ability of FCI to detect active disease in patients with PS.

Conditions

• Inflammatory Bowel Diseases
• Proctosigmoiditis

Interventions

Type	Name	Description
DEVICE	Field-cycling imaging (FCI)	FCI scan

Timeline

• Start date: 2024-03-01
• Primary completion: 2024-03-01
• Completion: 2024-03-31
• First posted: 2023-04-18
• Last updated: 2024-05-14

Locations

1 site across 1 country: United Kingdom