Trials / Completed
CompletedNCT05817149
Perioperative Examination of Inflammatory Markers in Relation to Sentinel Lymph Node Biopsy in Patients With Melanoma; a Pilot Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (actual)
- Sponsor
- Aalborg University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
We want to test if an association between sentinel lymph node biopsy (SLBN) and a systemic inflammatory response can be made.
Detailed description
Sentinel lymph node biopsy (SLBN) is essential in staging melanoma and properly selecting patients for adjuvant immunotherapy. However, surgically induced inflammation can potentially aid in progression of remaining malignant cells and affect prognosis. The inflammatory marker neutrophil-to-lymphocyte ratio (NLR) is also a negative prognostic and predictive marker in serval malignancies, among melanoma. However, it is not yet established if SLNB induces a systemic inflammatory response.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Blood samples | Blood samples |
Timeline
- Start date
- 2021-06-22
- Primary completion
- 2021-10-06
- Completion
- 2022-01-20
- First posted
- 2023-04-18
- Last updated
- 2023-04-18
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT05817149. Inclusion in this directory is not an endorsement.