NCT05815576

Biomechanics and Intrinsic Foot Muscle Roles in Subjects With Chronic Ankle Instability

Lower Limb (Patho-)Mechanical Joint Contact Forces and Intrinsic Foot Muscle Properties in Subjects With Lateral Ankle Sprain and Chronic Ankle Instability

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Université Catholique de Louvain · Academic / Other
• Sex: Male
• Age: 18 Years – 44 Years
• Healthy volunteers: Accepted

Summary

The current study involves a prospective interventional study that primarily intends to compare foot joint loadings of participants with chronic ankle instability (CAI) with those of subjects who recovered after an ankle sprain (LAS copers) and healthy controls during running and more challenging tasks. This study further aims to explore the impact of foot muscle properties and fatigue on the same biomechanical outcomes. Therefore, the investigators will recruit 72 participants (24 per group) aged from 18 to 44 years. Each of them will come only once to the CMAL laboratory (UZ Leuven, Pellenberg).

Conditions

• Chronic Ankle Instability
• Lateral Ankle Sprain

Interventions

Type	Name	Description
BEHAVIORAL	Intrinsic foot muscle fatigue	Electrostimulation will be delivered through electrodes placed on the abductor hallucis (NOT invasive). The investigators plan 4 sets of 4 minutes of repeated contractions (electrostimulation + voluntary contraction).

Timeline

• Start date: 2023-02-03
• Primary completion: 2025-02-17
• Completion: 2025-02-17
• First posted: 2023-04-18
• Last updated: 2025-09-02

Locations

1 site across 1 country: Belgium