Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT05815186

Ladarixin With Sotorasib in Advanced NSCLC - Phase II

Phase II Study of Ladarixin and Sotorasib In Advanced KRAS G12C Mutant Non-Small Cell Lung Cancer (NSCLC)

Status
Withdrawn
Phase
Phase 2
Study type
Interventional
Enrollment
0 (actual)
Sponsor
NYU Langone Health · Academic / Other
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

Study record has been combined with NCT05815173. See NCT05815173 for summary.

Conditions

Interventions

TypeNameDescription
DRUGSotorasibSotorasib administered at the approved dose of 960mg PO once daily over 21-day treatment cycles
DRUGLadarixinLadarixin administered twice-daily at the recommended phase II dose (RP2D) (determined in the phase I portion of this trial) over 21-day treatment cycles.

Timeline

Start date
2024-04-01
Primary completion
2025-04-01
Completion
2026-04-01
First posted
2023-04-18
Last updated
2024-03-29

Locations

6 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05815186. Inclusion in this directory is not an endorsement.