Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05814354

SHR-A1811 Versus Investigator's Chemotherapy in Recurrent/Metastatic Breast Cancer Clinical Trial

A Randomized, Open, Parallel-controlled, Multicenter Phase III Trial of SHR-A1811 Versus Investigator Chemotherapy in HER2-low Expressing Recurrent/Metastatic Breast Cancer

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
530 (estimated)
Sponsor
Jiangsu HengRui Medicine Co., Ltd. · Industry
Sex
Female
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The aim of this study was to evaluate whether the progression-free survival of SHR-A1811 was superior to investigator-selected chemotherapy in patients with HER2-low recurrent/metastatic breast cancer. To evaluate whether SHR-A1811 is superior to investigator-selected chemotherapy in patients with HER2-low recurrent/metastatic breast cancer.

Conditions

Interventions

TypeNameDescription
DRUGSHR-A1811SHR-A1811 is a lyophilized powder for injection intravenously. Administered according to label, as one option for Physician's Choice.
DRUGCapecitabine/Eribulin/Gemcitabine/Paclitaxel/Nab-paclitaxelAdministered according to label, as one option for Physician's Choice (determined before randomization).

Timeline

Start date
2023-06-30
Primary completion
2025-01-30
Completion
2026-06-30
First posted
2023-04-14
Last updated
2023-07-20

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05814354. Inclusion in this directory is not an endorsement.