NCT05812872

Alveolar Ridge Preservation Using Different Bone Substitutes

The Effect of Allograft, Toothgraft, Alloplast on Alveolar Ridge Preservation

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 20 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The primary objective of this study was to compare the efficacy of using allograft, autogenous tooth graft, and beta-tricalcium phosphate for alveolar ridge preservation (ARP) by examining the alveolar ridge height and width at baseline and 3 months after the ARP both clinically and radiographically. The secondary objective was to evaluate the quality of the newly formed bone using histomorphometric analysis.

Detailed description

This randomized controlled clinical trial included thirty patients. ARP was performed using either Allograft (Allograft group n=10), Tooth graft (Toothgraft group n=10), and beta tri-calcium- phosphate (beta tri-calcium group n=10). Changes in alveolar ridge dimensions were evaluated clinically and radiographically using cone beam computed tomography at baseline and 3 months. Core bone biopsy samples were obtained 3 months post-extraction during implant placement for histomorphometric analysis.

Conditions

• Alveolar Ridge Enlargement

Interventions

Type	Name	Description
DRUG	Toothgraft	Particulate dentin
DRUG	Allograft	Mineralized corticocancellous allograft
DRUG	Alloplast	Beta tri-calcuim phosphate

Timeline

• Start date: 2017-06-20
• Primary completion: 2018-09-23
• Completion: 2019-01-20
• First posted: 2023-04-14
• Last updated: 2023-04-19

Locations

1 site across 1 country: Egypt