NCT05812248

Prediction of Vascular Events After Major Non-Cardiac Surgery : an Observational Prospective Cohort Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 20,000 (estimated)
• Sponsor: Nanfang Hospital, Southern Medical University · Academic / Other
• Sex: All
• Age: 45 Years
• Healthy volunteers: Not accepted

Summary

This observational study includes patients at medium-to-high cardiovascular risks undergoing major noncardiac surgery, measures their baseline demographic and clinical characteristics, preoperative cardiac biomarkers and intraoperative surgery/anesthesia related data, and screens them for the occurrence of myocardial injury and major adverse cardiac events after surgery. The primary aim is to develop and validate a pre- and an immediate postoperative prediction model for occurrence of major adverse cardiac events.

Conditions

• Noncardiac Surgery

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Perioperative cardiac biomarker measurement	High-sensitivity cardiac troponin T is measured within 7 days prior to surgery and at day 1 and day 2 after surgery. N-terminal pro-B-type natriuretic peptide is measured within 7 days before surgery.

Timeline

• Start date: 2022-07-01
• Primary completion: 2027-11-01
• Completion: 2027-12-01
• First posted: 2023-04-13
• Last updated: 2024-09-19

Locations

1 site across 1 country: China