Trials / Completed
CompletedNCT05809947
Mechanisms of Tissue Repair After Muscle Injury and Tendon Strain
Regulation of Human Tendon and Skeletal Muscle Protein Turnover Following Tissue Injury: Mechanisms Behind Regeneration and Injury Preventive Adaptations
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 25 (actual)
- Sponsor
- Bispebjerg Hospital · Academic / Other
- Sex
- Male
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Accepted
Summary
The study is a 5-week human study including 24 18-35 year old healthy men. Each participant will have muscle injury and tendon strain induced in one leg using neuromuscular electrical stimulation in conjunction with forced lengthening contractions. The investigators will monitor the recovery from injury/strain over a 4 week period, in which half of the subjects will receive growth hormone (somatropin) to stimulate the connective tissue synthesis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Neuromuscular electrical stimulation | One bout of neuromuscular electrical stimulation in conjunction with forced lengthening contractions on one leg |
Timeline
- Start date
- 2023-04-11
- Primary completion
- 2024-01-03
- Completion
- 2024-01-03
- First posted
- 2023-04-12
- Last updated
- 2024-01-09
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT05809947. Inclusion in this directory is not an endorsement.