Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT05809583

Define Predictors of Response to Ozanimod in UC Discovering Biomarkers in the Management of Ulcerative Colitis

Applying Precision Medicine to Define Predictors of Response to Ozanimod and Discovering Biomarkers in the Management of Ulcerative Colitis Using 7,000 Protein SOMAscan

Status
Withdrawn
Phase
Study type
Observational
Enrollment
0 (actual)
Sponsor
Beth Israel Deaconess Medical Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A diagnostic tool that identifies biomarkers that predict response prior to and during induction of ozanimod will have a major impact on improving outcomes in UC patients. Using SOMAscan from SomaLogic (Boulder, CO), our study aims to discover serum protein biomarkers in UC patients that predict response to ozanimod and to gain insight into the pathophysiological mechanisms underlying ozanimod response.

Conditions

Interventions

TypeNameDescription
DRUGOzanimodPatients with established diagnosis of UC starting ozanimod therapy as part of their clinical care

Timeline

Start date
2023-04-12
Primary completion
2024-12-01
Completion
2024-12-01
First posted
2023-04-12
Last updated
2025-06-04

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05809583. Inclusion in this directory is not an endorsement.

Define Predictors of Response to Ozanimod in UC Discovering Biomarkers in the Management of Ulcerative Colitis (NCT05809583) · Clinical Trials Directory