Trials / Recruiting
RecruitingNCT05809284
Determining the Mechanisms of Loss of CAR T Cell Persistence
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- University College, London · Academic / Other
- Sex
- All
- Age
- 25 Years
- Healthy volunteers
- Not accepted
Summary
A prospective observational study of pediatric and young adult acute lymphoblastic leukaemia (ALL) patients treated with CD19 chimeric antigen receptor T-cells (CAR-T cells). The study will examine changes in CAR-T persistence over time and causal factors.
Conditions
- Acute Lymphoblastic Leukemia With Failed Remission
- Acute Lymphoblastic Leukemia Not Having Achieved Remission
- Acute Lymphoblastic Leukemia, Pediatric
- Acute Lymphoblastic Leukemia, Adult
- Acute Lymphoblastic Leukemia, in Relapse
Timeline
- Start date
- 2023-10-18
- Primary completion
- 2025-12-01
- Completion
- 2025-12-01
- First posted
- 2023-04-12
- Last updated
- 2024-05-23
Locations
3 sites across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT05809284. Inclusion in this directory is not an endorsement.