Trials / Completed
CompletedNCT05808023
Dose-dependent FODMAP Reintroduction in IBS
Dose-dependent Individual FODMAPs (Mannitol and Fructans) Reintroduction in Patients With Irritable Bowel Syndrome
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 45 (actual)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to evaluate whether symptom recurrence, after successful FODMAP elimination, is dose-dependent in patients with IBS. The effect of a blinded reintroduction of FODMAP powders fructans and mannitol will be investigated in a crossover dose-escalation scheme for the identification of the eliciting dose in individual patients. The reintroduction of FODMAPs is performed after a successful elimination by the LFD.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | FODMAP powder reintroduction | The FODMAP powders will be reintroduced in three different doses, each for three consecutive days. |
Timeline
- Start date
- 2023-04-01
- Primary completion
- 2025-08-25
- Completion
- 2025-08-25
- First posted
- 2023-04-11
- Last updated
- 2026-03-20
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT05808023. Inclusion in this directory is not an endorsement.