NCT05806944

Transcranial Magnetic Stimulation for Binge Eating Disorder

Evaluation of Active Emotional State on the Efficacy of Transcranial Magnetic Stimulation

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: University of Southern California · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Not accepted

Summary

The primary goal of this study is to elucidate the impact of disorder provocation on the efficacy of TMS for the treatment of BED. In order to meet this objective, the investigators propose to evaluate this relationship in using a crossover study. Secondary objectives of this study include determining whether TMS with or without BED symptom provocation has effects in altering neurophysiology as detected by fMRI.

Detailed description

Current literature has demonstrated that transcranial magnetic stimulation (TMS) targeting the dorsolateral prefrontal cortex (DLPFC) has some efficacy in treating binge eating disorder. The investigators believe that TMS may be beneficial in the treatment of binge eating disorder. The purpose of this study is to determine whether TMS has efficacy for binge eating disorder and if symptom provocation affects treatment. This study will be conducted as a pilot study in the Keck Hospital clinics. 32 adult patients with a clinical diagnosis of binge eating disorder will be recruited.

Conditions

• Binge-Eating Disorder

Interventions

Type	Name	Description
DEVICE	TMS followed by Sham TMS	double blinded crossover schedule in which participants will undergo TMS and assessment in one visit, followed by sham-TMS and assessment the next visit.
DEVICE	Sham TMS followed by TMS	double blinded crossover schedule in which participants will undergo sham TMS and assessment in one visit, followed by TMS and assessment the next visit.

Timeline

• Start date: 2023-12-15
• Primary completion: 2024-12-15
• Completion: 2024-12-15
• First posted: 2023-04-10
• Last updated: 2023-12-13

Regulatory

• FDA-regulated device study