NCT05805683

Calcitonin Therapy on Incidence and Severity of Neuropathic Pain After Spinal Cord Injury

Effect of Early Calcitonin Therapy on Incidence and Severity of Neuropathic Pain After Spinal Cord Injury

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This prospective randomized double blinded study will be conducted to evaluate the effect of early pharmacologic intervention with calcitonin on the incidence or the severity of neuropathic pain after spinal cord injury

Detailed description

Pain after spinal cord injury can be classified into five categories: musculoskeletal, visceral, at-level, above-level, and below-level neuropathic pain. Calcitonin has previously been shown to be effective in the management of acute pain following amputation, vertebral fractures and other neuropathic conditions. Also it was used in a previous study to prevent complex regional pain syndrome in severe hemiplegic patients after stroke

Conditions

• Calcitonin
• Neuropathic Pain
• Spinal Cord Injury

Interventions

Type	Name	Description
DRUG	Calcitonin	patients in this group will receive 100 IU (1 ml) of calcitonin subcutaneously per day for 2 weeks starting within 48 hours after injury.
DRUG	Placebo	patients in this group will receive 1 ml of saline placebo solution subcutaneously per day for 2 weeks starting within 48 hours after injury.

Timeline

• Start date: 2023-05-01
• Primary completion: 2026-05-01
• Completion: 2027-05-01
• First posted: 2023-04-10
• Last updated: 2025-05-06

Locations

1 site across 1 country: Egypt