Trials / Recruiting
RecruitingNCT05801380
Monitoring Drug Efficacy in Patients with Alzheimer's Disease
Monitoring Drug Efficacy Through Multi-omics Research Initiative in Alzheimer's Disease
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- University of the Philippines · Academic / Other
- Sex
- All
- Age
- 65 Years
- Healthy volunteers
- Not accepted
Summary
This study will explore the different factors associated with drug response to acetylcholinesterase (AChE) inhibitor (donepezil) and NMDA receptor antagonist (memantine) in patients with Alzheimer's Disease.
Detailed description
These patients will be grouped according to the medications prescribed by their attending physician at baseline, 3rd month, and 6th month of follow up: 1. Alzheimer's Disease patients given AChE inhibitor monotherapy 2. Alzheimer's Disease patients given combination therapy of AChE inhibitor and NMDA receptor antagonist They will be observed for treatment response for up to 6 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | AChE inhibitor monotherapy | This is a drug treatment using Donepezil only |
| DRUG | AChE inhibitor and NMDA receptor antagonist combination therapy | This is a drug treatment combining Donepezil and Memantine |
Timeline
- Start date
- 2022-02-14
- Primary completion
- 2026-02-14
- Completion
- 2026-02-14
- First posted
- 2023-04-06
- Last updated
- 2025-01-07
Locations
1 site across 1 country: Philippines
Source: ClinicalTrials.gov record NCT05801380. Inclusion in this directory is not an endorsement.