NCT05799768

Ketogenic Diet in Rheumatoid Arthritis (RA)

Ketogenic Diet Intervention in Patients With Rheumatoid Arthritis (RA): a Pilot Study

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (estimated)
• Sponsor: University of Oklahoma · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This is a 6-week ketogenic diet (KD) intervention where participants with rheumatoid arthritis (RA) will follow a KD plan, supervised and monitored by a dietician. Participants will be provided extensive educational and ongoing support on the KD, including personalized coaching with the ability to text a dietitian at any time and expect a response within 12 hours. Diet adherence and progress will be assessed daily using at-home blood ketone/glucose monitors, along with diet records. Participants will fill out health related questionnaires and undergo assessments of body composition, RA disease activity. This study also includes blood draws and fat biopsy of the abdominal region.

Conditions

• Rheumatoid Arthritis
• Inflammation
• Obesity
• Ketogenic Dieting
• Metabolic Syndrome

Interventions

Type	Name	Description
BEHAVIORAL	Ketogenic diet	Ketogenic diet counseling

Timeline

• Start date: 2023-04-20
• Primary completion: 2028-12-31
• Completion: 2029-12-31
• First posted: 2023-04-05
• Last updated: 2024-02-07

Locations

1 site across 1 country: United States