NCT05799417

Brain Oscillatory Signatures of Auditory Stimuli Across Different Vigilance and Sedation States

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Insel Gruppe AG, University Hospital Bern · Academic / Other
• Sex: All
• Age: 18 Years – 84 Years
• Healthy volunteers: Not accepted

Summary

The investigators want to explore how presenting acoustic stimuli influences brain oscillatory signatures and heart rhythm- dynamics across different vigilance and sedation states. The investigators will administer acoustic stimuli during sedation and anaesthesia while brain activity and heart activity are being recorded by electroencephalogram and electrocardiogram. On the day following anaesthesia an optional nap/sleep period's EEG and ECG will be recorded. During this short sleep, patients will again be exposed to acoustic stimuli. The recorded EEG and ECG will be compared intra-and inter-individually to recordings from sedation and anaesthesia.

Conditions

• Anesthesia
• Sleep

Interventions

Type	Name	Description
OTHER	Acoustic stimuli	During different states of sedation/anaesthesia and sleep, acoustic stimuli will be presented and compared to a within-subject baseline.

Timeline

• Start date: 2023-02-28
• Primary completion: 2023-11-01
• Completion: 2023-11-01
• First posted: 2023-04-05
• Last updated: 2023-04-05

Locations

1 site across 1 country: Switzerland