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AvailableNCT05795361

Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome

Post-trial Access Program: Idursulfase-IT (HGT-2310) in Conjunction With Intravenous Elaprase® in Pediatric and Adult Patients With Hunter Syndrome and Cognitive Impairment

Status
Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
Takeda · Industry
Sex
Male
Age
Healthy volunteers
Not accepted

Summary

As the HGT-HIT-046 (NCT01506141) and SHP609-302 (NCT02412787) studies are completed and closed, this post-trial access (PTA) program provides TAK-609 to participants in these studies for whom the benefit:risk ratio of continued treatment with idursulfase-IT remains positive.

Conditions

Interventions

TypeNameDescription
DRUGIdursulfase-ITParticipants will continue to receive the same dose of idursulfase-IT, once monthly, that was administered during the HGT-HIT-046 \[NCT01506141\] or SHP609-302 \[NCT02412787\] study \[10mg or 30mg\] along with intravenous (IV) infusions of standard-of-care therapy Elaprase via intrathecal drug delivery device (IDDD) or lumbar punctures.

Timeline

First posted
2023-04-03
Last updated
2026-04-13

Locations

22 sites across 5 countries: United States, Australia, Mexico, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT05795361. Inclusion in this directory is not an endorsement.

Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome (NCT05795361) · Clinical Trials Directory