NCT05790525

Effect of Oral Helicobacter Pylori Infection on the Efficacy of Gastroluminal Helicobacter Pylori Eradication Therapy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Xijing Hospital of Digestive Diseases · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to assess the effect of oral Helicobacter pylori infection on the efficacy of gastric Helicobacter pylori infection eradication. Patients diagnosed with gastric Helicobacter pylori infection are tested for oral Helicobacter pylori and given standard bismuth quadruple therapy, with a urea breath test, a rapid urease test, or a Helicobacter pylori stool antigen test to confirm gastric Helicobacter pylori eradication at week 6 follow-up, and an oral Helicobacter pylori test kit to confirm oral Helicobacter pylori eradication.

Conditions

• Helicobacter Pylori

Interventions

Type	Name	Description
DRUG	Standard bismuth quadruple	Use the standard bismuth quadruple regimen recommended by the latest Chinese guidelines

Timeline

• Start date: 2022-11-22
• Primary completion: 2023-09-01
• Completion: 2023-11-01
• First posted: 2023-03-30
• Last updated: 2025-07-03

Locations

1 site across 1 country: China