Trials / Unknown
UnknownNCT05787769
A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 96 (estimated)
- Sponsor
- Mansoura University · Academic / Other
- Sex
- Male
- Age
- 30 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to evaluate the efficacy and safety of intracavernosal injection of PRP in patients with moderate to severe ED.
Conditions
- Erectile Dysfunction Following Radiation Therapy
- Phosphodiesterase Inhibitor Adverse Reaction
- Platelet- Rich Plasma (PRP)
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | P shot arm ( Autologous Platelet Rich Plasma) | Autologous Platelet Rich Plasma + placebo tab Each injection session will consist of a total of 10 mL PRP infused slowly over a 2-minute period; 5 mL each injected to the right and left corpus cavernosum |
| DRUG | PDE5i arm | Patients will be treated by tadalafil 5 mg tablet daily in addition to four Tadalafil 5 mg tablet 3 hours before intercourse on demand in addition to placebo injection. Each injection session will consist of a total of 10 mL saline solution infused slowly over a 2-minute period; 5 mL each injected to the right and left corpus cavernosum. |
Timeline
- Start date
- 2023-03-01
- Primary completion
- 2025-01-25
- Completion
- 2025-01-25
- First posted
- 2023-03-28
- Last updated
- 2023-03-28
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05787769. Inclusion in this directory is not an endorsement.