Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05786443

Safety and Efficacy of Empagliflozin in Hemodialysis

A Phase II, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Assess the Safety, Tolerability, and Preliminary Efficacy of Empagliflozin Among Patients Initiating Hemodialysis for the Treatment of End-Stage Kidney Disease

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
60 (estimated)
Sponsor
NYU Langone Health · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A 12-week, phase II, randomized, double-blind, placebo-controlled, multi-center study to assess the safety, tolerability, and preliminary efficacy of empagliflozin versus placebo among patients initiating hemodialysis (n=60) for the treatment of end-stage kidney disease.

Conditions

Interventions

TypeNameDescription
DRUGEmpagliflozin 10 MGSodium glucose cotransporter 2 inhibitor (SGLT2i) dosed once-daily over 12 weeks. Administered as oral tablet.
DRUGPlaceboEmpagliflozin-matching placebo dosed once-daily over 12 weeks. Administered as oral tablet.

Timeline

Start date
2024-01-31
Primary completion
2026-12-30
Completion
2026-12-30
First posted
2023-03-27
Last updated
2025-12-04

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05786443. Inclusion in this directory is not an endorsement.