NCT05786274

Predicting Cerebrovascular Adverse Events Post Cardiac Surgery

Predicting Cerebrovascular Adverse Events Post Cardiac Surgery With Cardiopulmonary Bypass by Means of Cerebral AutoreguLation Indices

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 104 (estimated)
• Sponsor: IRCCS Policlinico S. Donato · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aims of this study are: i) to assess cerebral autoregulation and autonomic control within the different phases of cardiac surgery with cardiopulmonary bypass; ii) to compare cerebral autoregulation measures derived via cerebral blood flow velocity estimated by transcranial Doppler device with simpler measurements derived from near infrared spectroscopy; iii) to develop a predictive model of postoperative cerebrovascular outcome (overt or silent stroke) based on the extracted indices.

Conditions

• Cardiac Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cerebral autoregulation monitoring	Perioperative characterization of cerebral autoregulation and autonomic function; characterization of adverse events after surgery

Timeline

• Start date: 2023-04-01
• Primary completion: 2026-03-31
• Completion: 2026-03-31
• First posted: 2023-03-27
• Last updated: 2025-03-28

Locations

1 site across 1 country: Italy