NCT05783258

Connective Tissue Graft From Tuberosity Area and L-PRF Associated With Coronally Advanced Flap for Root Coverage

Comparative Evaluation of the Coronally Advanced Flap (CAF) Using a Connective Tissue Graft From the Tuberosity (tCTG) or L-PRF Membranes: a Randomized Controlled Clinical Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: G. d'Annunzio University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the present randomized controlled clinical study is to compare the efficacy of subepithelial connective tissue graft harvested from the maxillary retromolar tubeosity area and L-PRF membranes in the treatment of RT1 recessions by coronally advanced flap. A total of 30 patients will be recruited and randomly assigned to the test group treated with CAF+tSCTG or the control group treated with (CAF+L-PRF). For each experimental site the parameters of gingival recession (GR), pocket depth (PD), clinical attachment level (CAL), keratinized gingiva width (KT) and gingival thickness (GT) will be analyzed at baseline (T0) and at 12 months after the surgical procedure (T1). In addition, was also evaluated the different morbidity of the two surgical techniques, using the VAS scale values recorded in the first 2 weeks following surgery. It was checked the Patient Related Esthetic Score and Dentine hypersensivite reduction.

Conditions

• Gingival Recession

Interventions

Type	Name	Description
PROCEDURE	Periodontal surgery with CAF+tSCTG	Coronally advanced flap and subepithelial connective tissue graft harvested from the maxillary tuberosity area.
PROCEDURE	Periodontal surgery with CAF+L-PRF	Coronally advanced flap and L-PRF membranes

Timeline

• Start date: 2022-06-13
• Primary completion: 2023-10-29
• Completion: 2023-10-29
• First posted: 2023-03-24
• Last updated: 2023-11-21

Locations

1 site across 1 country: Italy