NCT05781295

Multicentre Randomised Study Comparing a Taurolidine Lock and a Standard Saline Lock in Paediatric Oncology

Multicentre Randomised Study Comparing a Taurolidine Lock and a Standard Saline Lock in the Primary Prevention of Catheter-related Endoluminal Infection in Paediatric Oncology.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 148 (estimated)
• Sponsor: Institut Curie · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

Interest of a Taurolidine lock at each catheter closure in the primary prevention of catheter-related endoluminal infection in paediatric oncology. Multicentric, controlled, randomized and double-blind label study.

Detailed description

The patient will be followed according to the type of pathology and the respective treatment protocol either Taurolock or physiological serum at each time cathter will be used.

Conditions

• Children
• Medical Device
• Primary Prevention
• Oncology

Interventions

Type	Name	Description
DEVICE	TaurolockTM	The patient will be followed up to a maximum of 6 months after randomization after have a TaurolockTM injected each time catheter will be used.
DEVICE	Physiological serum	The patient will be followed up to a maximum of 6 months after randomization after have a Physiological serum injected each time catheter will be used.

Timeline

• Start date: 2024-01-19
• Primary completion: 2028-07-23
• Completion: 2028-07-23
• First posted: 2023-03-23
• Last updated: 2026-02-20

Locations

5 sites across 1 country: France