Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05779631

Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm

Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm (BladParadigm)

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
360 (estimated)
Sponsor
Radboud University Medical Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A two-arm multicenter randomised controlled trial, comparing progression free survival, time to definitive treatment and cost-effectiveness of the standard of care (TURBT) and mpMRI followed by same-day cystoscopic bladder biopsy for diagnosis of patients with suspicion of muscle-invasive bladder cancer.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTmpMRI plus a same-day cystoscopic bladder biopsympMRI plus a same-day cystoscopic bladder biopsy
PROCEDURETURBTTransurethral resection of the bladder tumor, blood withdrawal shortly before and after TURBT

Timeline

Start date
2023-12-06
Primary completion
2028-12-01
Completion
2031-06-01
First posted
2023-03-22
Last updated
2026-01-08

Locations

19 sites across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT05779631. Inclusion in this directory is not an endorsement.

Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm (NCT05779631) · Clinical Trials Directory