Trials / Terminated
TerminatedNCT05778695
Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Ketones
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 16 (actual)
- Sponsor
- University of Michigan · Academic / Other
- Sex
- All
- Age
- 45 Years
- Healthy volunteers
- Accepted
Summary
Small exploratory open-label pilot study to assess supplementation of a ketone ester (KetoneAid) as a potential therapy for persons with Parkinson disease (PD), Parkinson Disease Dementia/Lewy Body Dementia (PDD/LBD), and healthy controls.
Detailed description
The overarching goal of this study is to investigate glucose metabolic, cognitive, clinical and imaging changes in persons with PD and PDD/LBD before and after a month supplementation of a ketone ester (KetoneAid) in a small open label exploratory clinical trial. Positive findings in this small exploratory pilot trial may support future target engagement studies of ketone supplementation in PD and normal adults.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Ketone Ester (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate | Ketone ester (KE) dietary supplement (KetoneAid) |
Timeline
- Start date
- 2023-03-09
- Primary completion
- 2023-10-04
- Completion
- 2023-10-04
- First posted
- 2023-03-21
- Last updated
- 2025-02-12
- Results posted
- 2025-02-12
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT05778695. Inclusion in this directory is not an endorsement.