Trials / Unknown
UnknownNCT05777148
Comparison of Efficacy in Removal of Advanced Glycation End Products (AGEs) Between Super High-flux Hemodialysis and Postdilution Online Hemodiafiltration: A Single-center, Prospective, Open-label, Crossover Randomized Controlled Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 22 (actual)
- Sponsor
- Mahidol University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this clinical trial is to compare efficacy in advanced glycation end products removal between Super high-flux Hemodialysis and high-volume post-dilution online hemodiafiltration. The main question it aims to answer are * Efficacy : endothelial dysfunction biomarker (AGEs) in super high-flux hemodialysis compared to online HDF * Safety profile : Dialysate albumin loss, Intradialytic complication Participants will be asked to randomized in 2 groups : Super high-flux HD or post dilution ol-HDF Researchers will compare SHF-HD and ol-HDF to see whether SHF-HD could remove AGEs better than ol-HDF
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | super high-flux hemodialysis | Super high-flux hemodialysis (SHF-HD) is hemodialysis using Super high-flux dialyzer for 24 week then crossover to post dilution online HDF (wash out period 4 weeks) |
| DEVICE | postdilution online hemodiafiltration | hemodialysis by post dilution online HDF technique for 24 week then crossover to super high-flux HD (wash out period 4 weeks) |
Timeline
- Start date
- 2022-04-04
- Primary completion
- 2023-06-30
- Completion
- 2023-06-30
- First posted
- 2023-03-21
- Last updated
- 2023-03-21
Locations
1 site across 1 country: Thailand
Source: ClinicalTrials.gov record NCT05777148. Inclusion in this directory is not an endorsement.