NCT05771467

Evaluation of Retinal Microvascular Change That May Develop in After Open Globe Injury

Evaluation of Retinal Microvascular Change That May Develop in After Open Globe Injury With Optical Coherence Tomography

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Akdeniz University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate posterior segment changes in the non-traumatic eye after open globe injury.

Detailed description

Globe injuries can be classified as either closed- or open-globe injuries, based on the integrity of the sclera and cornea. Open-globe injury (OGI) is characterized by a full-thickness wound of the ocular wall. As one of the most severe forms of ocular trauma, open-globe injury (OGI) causes significant vision loss. Timely and meticulous repair of these injuries can improve patient outcomes. OGI by rupture often occurs at the weakest point of the eye wall, which may or may not be at the actual injury site. The rupture site is most commonly found in the sclera concentric to the limbus, just posterior to the insertion of the extraocular muscles. After trauma, changes may occur in the non-trauma eye. Retinal and choroidal circulation may change as a result of adaptation mechanisms. In this study, we evaluated the vascular densities of the control group and post-traumatic non-trauma eye.

Conditions

• Eye Injury Trauma

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Comprehensive Ophthalmologic Examination	Measurements of best-corrected visual acuity, refractive error, intraocular pressure, axial length, slit lamp examination of the anterior segment, dilated fundus examination, and anterior segment parameters, optical coherence tomography angiography (OCTA)

Timeline

• Start date: 2024-03-02
• Primary completion: 2024-09-02
• Completion: 2024-09-02
• First posted: 2023-03-16
• Last updated: 2025-01-16
• Results posted: 2025-01-16

Locations

2 sites across 1 country: Turkey (Türkiye)