NCT05771116

Erector Spinae Catheter Versus Paravertebral Catheter for Postoperative Analgesia in Cancer Patients Post Mastectomies

Erector Spinae Catheter Versus Paravertebral Catheter for Pain Management in Modified Radical Mastectomy for Cancer Patients: A Randomized Double-Blind Non-inferiority Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: National Cancer Institute, Egypt · Academic / Other
• Sex: Female
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

All patients admitted in National Cancer institute, Cairo University for breast surgeries will be investigated for inclusion criteria in the current study. And will be enrolled if fulfilled the criteria into 2 groups .70 patients will be included in this prospective randomized study. The patients will be allocated into two groups: the ESPB group (group E, n = 35) , and the paravertebral group (group P, n =35) * All patients will do Ultrasound-guided ESPB for group E and PVB for group P before receiving general anesthesia * Postoperatively Patients in both groups will receive intravenous morphine 3 mg as rescue analgesic

Detailed description

* 70patients will be included in this prospective randomized study. The patients will be allocated into two groups: the ESPB group (group E, n = 35) , and the paravertebral group (group P, n =35) * All patients will do Ultrasound-guided ESPB for group E and PVB for group P before receiving GA * Postoperatively Patients in both groups will receive intravenous morphine 3 mg as rescue analgesic. * Random numbers were generated using a computer-generated randomization code and were sealed in an opaque envelope. Randomization was conducted by a person who was not involved in the study. * An independent observer who was blind to the group assignment checked the intraoperative and postoperative data. * VAS pain score immediately postoperative and at 2,4,6, 8,12,18,24,36 ,48hrs.postoperative.

Conditions

• Post Operative Pain

Interventions

Type	Name	Description
PROCEDURE	ERECTOR SPINAE PLANE BLOCK and PARAVERTEBRAL BLOCK:	catheter will be placed for ERECTOR SPINAE PLANE BLOCK
PROCEDURE	PARAVERTEBRAL BLOCK:	catheter will be placed for PARAVERTEBRAL BLOCK

Timeline

• Start date: 2023-01-01
• Primary completion: 2023-07-15
• Completion: 2023-07-15
• First posted: 2023-03-16
• Last updated: 2023-07-19

Locations

1 site across 1 country: Egypt