NCT05768776

Outpatient Holmium LASER Enucleation of the Prostate: Benefit of MOSES(TM) 2.0 Technology

To Compare the Effectiveness of the MOSES 2.0 Technology to the Non-MOSES Technology on the Success Rate of Holmium LASER Enucleation of the Prostate (HoLEP) Performed on an Outpatient Basis in the Context of Benign Prostatic Hypertrophy.

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: University Hospital, Bordeaux · Academic / Other
• Sex: Male
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare the success rate of outpatient surgery after holmium LASER enucleation of the prostate (HoLEP) for the treatment of BPH with and without the use of the MOSES 2.0 effect.

Detailed description

HoLEP is in the process of becoming the new reference surgical treatment for BPH with the main advantages over monopolar transurethral resection (TURPm) and high approach adenomectomy (AVH): the significant reduction in morbidity perioperative period and therefore the reduction in the length of hospital stay. This reduction in length of stay has led to the development of outpatient care with encouraging results. The main cause of discharge failure on D0 is the persistence of postoperative hematuria requiring maintenance of bladder irrigation. MOSESTM 2.0 technology has the advantage of better hemostasis compared to the LASER LP100 currently used. The objective of this study is to evaluate the influence of MOSESTM 2.0 technology on the outpatient success rate in patients operated on for HoLEP for BPH.

Conditions

• Benign Prostatic Hypertrophy
• Holmium Laser Enucleation of the Prostate

Interventions

Type	Name	Description
PROCEDURE	HoLEP patients without MOSES(TM) 2.0 effect (open label)	HoLEP surgery for the treatment of Benign Prostate Hyperthrophy, without using MOSES technology
PROCEDURE	HoLEP patients with MOSES(TM) 2.0 effect (open label)	HoLEP surgery for the treatment of Benign Prostate Hyperthrophy, with the use of MOSES technology

Timeline

• Start date: 2023-06-28
• Primary completion: 2025-07-01
• Completion: 2025-07-01
• First posted: 2023-03-14
• Last updated: 2025-06-25

Locations

1 site across 1 country: France