NCT05768165

High-intensity Interval Exercise in Rheumatoid Arthritis

Expected Health Benefits on Cardiovascular Function, Inflammation and Quality of Life With High-intensity Interval Exercise for Patients With Rheumatoid Arthritis

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 87 (actual)
• Sponsor: Vastra Gotaland Region · Other Government
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Cardiovascular performance and overall fitness can be improved by high-intensity aerobic activity, and these benefits may be achievable by persons with rheumatic diseases. The investigators hypothesize that a 12-week high-intensity interval exercise program will provide substantial improvements in cardiovascular function, inflammation and symptoms affecting quality of life.

Conditions

• Rheumatoid Arthritis

Interventions

Type	Name	Description
BEHAVIORAL	High intensity exercise	Twelve weeks of supervised high intensity aerobic and resistance exercise including two sessions/week, one additional session of the patient´s own choice, non-supervised. The target of the high intensity intervals (HIIT) is 90%-95% of maximum heart rate alternated with recovery phases at 70% of maximal heart rate. The resistance exercise session of large muscle groups: 8-10 repetitions, 2-3 sets. Exercise guidance follows principles of self-efficacy and person-centeredness.

Timeline

• Start date: 2021-08-16
• Primary completion: 2023-06-30
• Completion: 2026-12-30
• First posted: 2023-03-14
• Last updated: 2025-12-22

Locations

2 sites across 1 country: Sweden