NCT05766332

Evaluating Clinical Evaluation Tools for Predicting Risk of Complications After Hematopoietic Stem Cell Transplant

Developing Novel Tools for Determining Risk of Respiratory Complications Following Hematopoietic Stem Cell Transplant

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 137 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study evaluates whether clinical evaluation tools such as the six-minute walk test, hand grip strength test, and gait speed test, are useful in predicting risk of complications in patients undergoing hematopoietic stem cell transplants (HCT). Being able to predict who is at increased risk of post-HCT complications can help better inform patients and providers on the risks and benefits of undergoing HCT and determine whether certain patients should have closer post-HCT monitoring due to an increased risk of complications.

Detailed description

PRIMARY OBJECTIVE: I. To develop novel pre-transplant tools for determining risk of post-HCT pulmonary complications. OUTLINE: This is an observational study. Patients undergo a clinical evaluation consisting of a six-minute walk test, hand grip strength test, and gait speed test on study. Patients' medical records are also reviewed for a year on study.

Conditions

• Hematopoietic and Lymphoid System Neoplasm
• Malignant Solid Neoplasm

Interventions

Type	Name	Description
OTHER	Clinical Evaluation	Undergo clinical evaluation
OTHER	Electronic Health Record Review	Medical records reviewed

Timeline

• Start date: 2021-08-02
• Primary completion: 2023-11-17
• Completion: 2023-11-17
• First posted: 2023-03-13
• Last updated: 2025-01-10

Locations

1 site across 1 country: United States