Trials / Unknown
UnknownNCT05765838
Combined Molecular Testing for Influenza, SARS-CoV-2, and RSV RNA From Different Upper Airway Specimens.
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 250 (estimated)
- Sponsor
- Rigshospitalet, Denmark · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
This is a comparative prospective diagnostic accuracy study reported according to the STARD guidelines. Citizens at an outpatient COVID19 test facility at Testcenter Danmark Valby will be invited to participate in the study on a volunteer basis. The enrolled participants will have the planned oropharyngeal swab performed in the test center and sent for a SARS-CoV-2 RT-PCR test at TestCenter Danmark, Statens Serum Institut, Copenhagen, Denmark as usual. Besides the planned oropharyngeal swab performed in the test center, the participants will have additional specimens collected in form of saliva, nasopharyngeal-, nasal-, and oropharyngeal swabs. These will all be used for the detection of nucleic acids from the four most common strains of influenza (B Yamagata, B Victoria, A H1N1 and A H3N2), SARS-CoV-2 and RSV A/B. Further we will measure immune mediating cytokines, chemokines, and interleukins in the different specimens. These analyses will be performed at Technical University of Denmark (DTU).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | (NPS right - Nasal swab left - OPS) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (NPS left - Nasal swab right - OPS) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (Nasal swab right - NPS left - OPS) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (Nasal swab left - NPS right - OPS) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (NPS right - OPS - Nasal swab left) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (NPS left - OPS - Nasal swab right) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (Nasal swab right - OPS - NPS left) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (Nasal swab left - OPS - NPS right) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (OPS - NPS right - Nasal swab left) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (OPS - NPS left - Nasal swab right) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (OPS - Nasal swab left - NPS right) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
| DIAGNOSTIC_TEST | (OPS - Nasal swab right - NPS left) | Collection of nasopharyngeal-, nasal-, and oropharyngeal swabs in randomized order |
Timeline
- Start date
- 2023-03-03
- Primary completion
- 2023-04-01
- Completion
- 2023-07-01
- First posted
- 2023-03-13
- Last updated
- 2023-03-28
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT05765838. Inclusion in this directory is not an endorsement.