NCT05762484

Efficacy of Laser Hair Removal Therapy in HS

The Efficacy of Laser Hair Removal Therapy in Patients With Mild to Moderate HS, a Randomized Controlled Trial.

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 58 (estimated)
• Sponsor: Erasmus Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hidradenitis suppurativa (HS) is a chronic, recurrent and debilitating inflammatory skin disorder, characterized by painful inflamed nodules, abscesses and tunnels in the skin folds such as the axilla, inguinal region and gluteal area. The primary event in HS is occlusion of the hair follicle. HS is a notoriously difficult to treat disease, because treatment options are limited and evidence based treatments are scarce. Prevention of diseases is an important topic in medicine. However, current clinical trials in HS are focusing on anti-inflammatory drugs in patients with severe HS, whereas prevention and treatment of patients with more common mild HS is neglected. Laser hair removal therapy is a non-invasive procedure with minimal treatment discomfort for patients. Previous limited studies have suggested positive results in favor of laser hair removal therapy in HS. We therefore hypothesize that hair depilation using laser hair removal therapy may prevent the formation of new lesions and flares of the disease. The objective is to assess the efficacy of laser hair removal therapy in patients with mild to moderate HS.

Conditions

• Hidradenitis Suppurativa, Acne Inversa

Interventions

Type	Name	Description
PROCEDURE	Nd:YAG laser hair removal	Using the Nd:YAG laser (cynergy), hair of the axillae will be removed.
DRUG	Clindamycin 1 % Topical Lotion	Clindamycin 1% lotion if needed

Timeline

• Start date: 2023-04-01
• Primary completion: 2024-12-01
• Completion: 2026-04-01
• First posted: 2023-03-09
• Last updated: 2023-03-09