NCT05762302

The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)

A Multicenter Randomized Controlled Trial to Establish the Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,316 (estimated)
• Sponsor: MeMed Diagnostics Ltd. · Industry
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

This is a Prospective, multi-center study enrolling adults subjects presented to the ED/Urgent care, with symptoms consistent with lower respiratory infection (LRTI). The reason of this study is to demonstrate the MeMed BV can help clinicians make decisions about using antibiotics in patients with lower respiratory track infections and see how it would impact clinical outcomes, antibiotics use, hospitalizations, ED clinicians find ways to improve health and medical care.

Detailed description

There will be a pre-study implementation phase (JUNO trial), in which approximately 250 patients will be recruited. Data obtained for these patients will not be included in the analysis. The purpose of the pre-study implementation phase is to enable the participating clinicians to become familiar with the MeMed BV test. An additional purpose is to test the design and operational assumptions before the subsequent JUPITER trial.

Conditions

• Lower Respiratory Tract Infection

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	MeMed BV test	Following the MeMed BV test result, the clinician will decide whether or not to prescribe an antibiotic for your condition

Timeline

• Start date: 2023-01-31
• Primary completion: 2026-02-01
• Completion: 2026-02-28
• First posted: 2023-03-09
• Last updated: 2026-01-21

Locations

10 sites across 2 countries: United States, Israel

Regulatory

• FDA-regulated device study