NCT05761938

A Study of Rituximab in Frontline Therapy for Glomerulonephritis

A Multicenter, Prospective, Real World Study of Rituximab in Frontline Therapy for Glomerulonephritis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: —

Summary

This study included patients with glomerulonephritis who planned to receive rituximab treatment, and observed the efficacy and safety of rituximab in different glomerulonephritis in the real world. According to the pathological types of glomerulonephritis, they were divided into two cohorts : membranous nephropathy ( MN ) group or minimal change disease / focal segmental glomerulosclerosis ( MCD / FSGS ) group.

Detailed description

A total of 100 patients with glomerulonephritis who planned to receive rituximab treatment were enrolled in the study. According to the pathological types of glomerulonephritis, they were divided into MN cohort and MCD / FSGS cohort, with 50 patients in each cohort. All eligible patients who meet the inclusion and exclusion criteria will be invited to participate in this study.

Conditions

• Glomerulonephritis

Timeline

• Start date: 2023-02-01
• Primary completion: 2024-12-01
• Completion: 2025-12-01
• First posted: 2023-03-09
• Last updated: 2023-03-09

Locations

5 sites across 1 country: China