NCT05759039

SHould You TransFer the Tubercle?

A Randomized Clinical Pilot Trial Comparing Isolated Medial Patellofemoral Ligament Reconstruction to Medial Patellofemoral Ligament Reconstruction Combined with Tibial Tubercle Osteotomy: SHould You TransFer the Tubercle (SHYFT)?

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Banff Sport Medicine Foundation · Academic / Other
• Sex: All
• Age: 13 Years – 30 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to investigate the role of tibial tubercle osteotomy (TTO) on the subjective and objective outcomes following medial patellofemoral ligament reconstruction (MPFL-R) in patients with an increased tibial tubercle-trochlear groove (TT-TG) distance with or without patella alta. This Pilot RCT will assess the feasibility of conducting this study for: 1. The ability to recruit study patients 2. Adherence to the study protocol 3. Completion rates of patient follow-up at a minimum of 12 months post-operative

Detailed description

For patients with recurrent lateral patellofemoral instability, a medial patellofemoral ligament reconstruction (MPFL-R) consistently provides significant improvements in symptoms, quality of life, and return to sport. During an MPFL-R the surgeon will place a soft tissue graft from the medial patella to the femur. The graft used to create the new MPFL can be autograft (usually hamstring tendon) or allograft. The tibial tubercle osteotomy (TTO) is a procedure designed to change the vector of the pull of the quadricep muscles by moving the insertion point of the patellar tendon. This is achieved by transferring the tendon with a block of bone to allow for consistent and reliable healing. The TTO is a versatile procedure that can move the patellar tendon insertion medially, anteriorly, or distally, or a combination of these directions. It can be used to correct a lateralized tibial tubercle or patella alta. Despite the association of an increased TT-TG distance with patellofemoral instability, it has been difficult to demonstrate a correlation with patient outcomes after patellar stabilisation surgery. In addition, studies have been unable to correlate the pre-operative presence of patella alta with clinical outcomes after MPFL-R. This randomized clinical pilot trial will randomly allocate patients with lateral patellofemoral instability and an elevated TT-TG distance with or without patella alta ato receive either an isolated MPFL-R or an MPFL-R in combination with a correcting TTO (medializing, distalizing, or a combination of both). Patients will be followed for two years post-operative with subjective outcome measures and objective clinical and functional testing. The study groups will be: 1. Isolated MPFL-R 2. MPFL-R with a TTO The primary outcome measures will be: 1. Number of study patients recruited 2. Adherence to the study protocol (number of protocol deviations) 3. Follow-up completion rates of study patients at a minimum of 12 months post-operative Secondary outcome measures include the Banff Patellar Instability Instrument 2.0 (BPII 2.0), functional testing, clinical assessment, complications, re-dislocation rate, post-operative pain scores, patient satisfaction, and patient-reported outcome scores. If feasibility is demonstrated via this Pilot RCT, a larger RCT will be designed to answer important questions on how to optimize outcomes and limit morbidity after MPFL-R.

Conditions

• Patellofemoral Dislocation
• Tibial Tubercle Osteotomy
• Medial Patellofemoral Ligament Reconstruction

Interventions

Type	Name	Description
PROCEDURE	Medial patellofemoral ligament reconstruction	Medial patellofemoral ligament reconstruction
PROCEDURE	Tibial tubercle osteotomy	Tibial tubercle osteotomy

Timeline

• Start date: 2023-09-01
• Primary completion: 2025-12-31
• Completion: 2026-09-01
• First posted: 2023-03-08
• Last updated: 2025-02-04

Locations

1 site across 1 country: Canada