Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05757102

A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

A Phase 3, 24-week, Randomized, Double-blind, Parallel-group Bayesian Dynamic Borrowing Study Comparing the Efficacy, Safety, Tolerability and Pharmacokinetics of FF/UMEC/VI With FF/VI in 12-17-year-old Participants With Inadequately Controlled Asthma on Stable Maintenance Therapy With ICS/LABA

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
292 (estimated)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
12 Years – 17 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compared with FF/VI after 24 weeks of treatment.

Conditions

Interventions

TypeNameDescription
DRUGFF/UMEC/VIFF/UMEC/VI will be administered.
DEVICEELLIPTAFF/UMEC/VI and FF/VI will be administered via ELLIPTA inhaler
DRUGFF/VIFF/VI will be administered.

Timeline

Start date
2023-04-25
Primary completion
2027-01-15
Completion
2027-01-15
First posted
2023-03-07
Last updated
2025-10-07

Locations

42 sites across 6 countries: United States, Argentina, Australia, Chile, New Zealand, South Korea

Regulatory

Source: ClinicalTrials.gov record NCT05757102. Inclusion in this directory is not an endorsement.