NCT05756244

PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism

A Prospective Cohort Study Evaluating Peripartum Anticoagulation Management Among Pregnant Women With Venous Thromboembolism and Its Impact on Patient Outcomes

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 825 (estimated)
• Sponsor: University of Calgary · Academic / Other
• Sex: Female
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The PREP and GO study is an international multicentre prospective cohort evaluating anticoagulation management strategies around labor and delivery and the postpartum period.

Detailed description

The goal of this study is to provide quality data using standardized outcome definitions on postpartum bleeding events, venous thromboembolism (VTE) risk, delivery experience outcomes and health care utilization for intrapartum and postpartum anticoagulation management among pregnant individuals on low-molecular-weight heparin (LMWH) for prevention of treatment of VTE.

Conditions

• Pregnancy Related
• Venous Thromboembolism

Timeline

• Start date: 2023-04-04
• Primary completion: 2029-06-30
• Completion: 2029-12-31
• First posted: 2023-03-06
• Last updated: 2025-11-28

Locations

14 sites across 5 countries: United States, Canada, Denmark, France, Switzerland