NCT05756049

Procalcitonin Protocol Use to Guide Antibiotic Therapy Duration in the Intensive Care Unit

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 208 (estimated)
• Sponsor: Methodist Health System · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Accepted

Summary

To compare and contrast antibiotic use and its effects on patient outcomes before and after the implementation of a PCT protocol in the ICU at Methodist Richardson Medical Center (MRMC).

Detailed description

Based on previous clinical trials, current literature supports the use of PCT levels in combination with clinical assessments to help determine optimal antibiotic therapy. On May 30, 2022, MRMC launched a PCT protocol in the ICU that allows clinical pharmacy specialists to order PCT levels in certain bacterial infections. In order to determine the effects of the protocol, a retrospective quasi-experimental review will be conducted

Conditions

• Comparing Antibiotic Duration of Therapy

Interventions

Type	Name	Description
OTHER	compare antibiotic duration of therapy	To compare antibiotic duration of therapy before and after the implementation of the PCT protocol in the ICU.

Timeline

• Start date: 2022-11-29
• Primary completion: 2024-11-29
• Completion: 2024-11-29
• First posted: 2023-03-06
• Last updated: 2024-03-27

Locations

1 site across 1 country: United States