NCT05755529

Effects of Low LH Serum Levels on Ovarian Pick-up Outcome

Effects of Low LH Serum Levels on Oocyte Retrieval, Fertilization Rate and Embryo Quality During Controlled Ovarian Stimulation: Results From a Prospective Cohort Analysis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 43 (estimated)
• Sponsor: University of Palermo · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Luteinizing hormone (LH) plays a key role for normal follicular development and oocyte maturation in controlled ovarian stimulation. In particular, LH stimulates the proliferation and differentiation of theca cells for the secretion of androgens, which synergistically increase the production of estrogen. This study aimed to investigate the effects of low LH concentrations on oocyte retrieval, fertilization and embryo development in patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). Patients undergoing IVF/ICSI were prospectively analyzed, subdividing them into three groups according to their age. Serum LH levels were evaluated at day 3, during stimulation (day 10) and before ovulation induction (day 12).

Conditions

• Infertility, Female
• ART

Timeline

• Start date: 2023-03-01
• Primary completion: 2023-03-01
• Completion: 2023-03-01
• First posted: 2023-03-06
• Last updated: 2023-03-06