NCT05751434

A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer

Phase 2 Trial of Exercise Therapy on Markers of Progression in Localized Prostate Cancer

• Status: Active Not Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to find out the effects of exercise therapy on indicators of prostate cancer in people with low-risk prostate cancer who are on active surveillance. The exercise therapy in this study will be regular home-based walking sessions on a treadmill, and that therapy will be assigned by an exercise physiologist (a medical professional who studies how exercise affects the human body). Some participants in this study will have the assigned exercise therapy, and some participants will participate in their usual exercise routines. Researchers will compare how the assigned exercise therapy and the usual exercise routines affect indicators of prostate cancer in participants. This study will not provide treatment for prostate cancer.

Conditions

• Prostate Cancer
• Prostate Adenocarcinoma
• Localized Prostate Carcinoma

Interventions

Type	Name	Description
BEHAVIORAL	Exercise Therapy	The intervention will consist of exercise therapy, individualized, walking delivered following a non-linear (i.e., exercise dose is continually altered and progressed in conjunction with appropriate rest/recovery sessions across the entire intervention period) dosing schedule, up to 5 individual treatment sessions/week to achieve a cumulative total duration of 225 to 300 mins/wk until the participant's next standard of care prostate biopsy (about 6-12 months).

Timeline

• Start date: 2023-02-10
• Primary completion: 2027-02-10
• Completion: 2027-02-10
• First posted: 2023-03-02
• Last updated: 2026-02-06

Locations

9 sites across 1 country: United States