NCT05748756

Bone Marrow Aspirate Concentrate in Treating Mandibular Cystic Defects

The Effect of Bone Marrow Aspirate Concentrate in the Treatment of Mandibular Cystic Defects (Randomized Clinical Trial)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Hams Hamed Abdelrahman · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Mandibular cystic defect healing is a complex process. Various methods have been developed to shorten the bone regeneration time and improve its quality. Autogenous grafting is the gold standard for filling cystic defects due to the osteogenesis property provided by the viable cells but is related to donor site morbidity. Allografts and Xenografts are used for the same purpose. However, the increased cost is their main disadvantage. Bone marrow aspirate concentrate is now used to enhance the healing and regeneration process in many areas of the body with no morbidity and low cost.

Conditions

• Mandible Cyst

Interventions

Type	Name	Description
OTHER	Enucleation and filling by Bone marrow aspirate	The iliac crest is palpated along its widest part forming the iliac tubercle ( 5-6 cm posterior to the anterior superior iliac spine), then a 5 mm incision is made 3-4 cm posterior to the ASIS directly on the crest. The needle is advanced between the outer and inner plates of the ileum for a 4-6 cm into the cancellous bone and 10 ml of bone marrow is aspirated. Bone marrow aspirate is processed by a dual centrifugation technique.
OTHER	Conventional enucleation only	patients were treated conventionally by enucleation and plain collagen sponge only.

Timeline

• Start date: 2022-01-19
• Primary completion: 2022-07-13
• Completion: 2022-07-17
• First posted: 2023-03-01
• Last updated: 2023-03-01

Locations

1 site across 1 country: Egypt